About ice syndrome, cogan-reese type

What is ice syndrome, cogan-reese type?

Cogan-Reese Syndrome is an extremely rare eye disorder characterized by a matted or smudged appearance to the surface of the iris; the development of small colored lumps on the iris (nodular iris nevi); the attachment of portions of the iris to the cornea (peripheral anterior synechiae); and/or increased pressure in the eye (glaucoma). Secondary glaucoma may lead to vision loss. This disorder most frequently appears in young and middle-aged females, usually affecting only one eye (unilateral) and developing slowly over time.

What are the symptoms for ice syndrome, cogan-reese type?

Symptoms may include a matted or smudged appearance to the surface of the iris; the development of small colored lumps on the iris (nodular iris nevi); the attachment of portions of the iris to the cornea (peripheral anterior synechiae); and/or increased pressure in the eye (glaucoma).

What are the causes for ice syndrome, cogan-reese type?

The exact cause of Cogan syndrome is unknown, but it’s likely an autoimmune condition. It’s also closely related to vasculitis, which refers to inflammation of your blood vessels. However, researchers aren’t clear on the relationship between the two conditions. There’s no evidence that Cogan syndrome is hereditary.

Cogan syndrome affects both men and women. It tends to start between the ages of 20 and 40.

What are the treatments for ice syndrome, cogan-reese type?

While it is not yet known how to keep Cogan-Reese syndrome from progressing, the glaucoma associated with the disease can be treated with medication. Additionally, corneal transplant can treat any corneal swelling. The National Eye Institute provides information on screening for glaucoma.

What are the risk factors for ice syndrome, cogan-reese type?

The ICE syndromes predominantly affect Caucasian, young to middle-aged women, and involve one eye. While there have been some cases of Cogan-Reese syndrome reported in children, the disease is typically observed in females in the mid-adult years. 

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