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Stay informed about the latest scientific discoveries in pain management through our curated collection of Pain Research Articles. Explore a wealth of information on treatment approaches, emerging interventional techniques, and scientific breakthroughs. Whether you're a healthcare professional or someone navigating the challenges of pain management, these articles provide valuable insights to inform your decisions.
Sponsored By- Acquired Class D -Lactamases
The Class D -lactamases have emerged as a prominent resistance mechanism against -lactam antibiotics that previously had efficacy against infections caused by pathogenic bacteria, especially by Acin... Read More
- A Novel Organo-Selenium Bandage that Inhibits Biofilm Development in a Wound by Gram-Positive and Gram-Negative Wound Pathogens
Biofilm formation in wounds is a serious problem which inhibits proper wound healing. One possible contributor to biofilm formation in a wound is the bacteria growing within the overlying bandage. To ... Read More
- A Point Prevalence Survey of Antibiotic Use in 18 Hospitals in Egypt
Inappropriate antibiotic use leads to increased risk of antibiotic resistance and other adverse outcomes. The objectives of the study were to determine the prevalence and characteristics of antibiotic... Read More
- Antimicrobial Peptide Resistance Mechanisms of Gram-Positive Bacteria
Antimicrobial peptides, or AMPs, play a significant role in many environments as a tool to remove competing organisms. In response, many bacteria have evolved mechanisms to resist these peptides and p... Read More
- Differential Susceptibility of Bacteria to Mouse Paneth Cell a-Defensins under Anaerobic Conditions
Small intestinal Paneth cells secrete -defensin peptides, termed cryptdins (Crps) in mice, into the intestinal lumen, where they confer immunity to oral infections and define the composition of the i... Read More
- Anti-Biofilm and Immunomodulatory Activities of Peptides That Inhibit Biofilms Formed by Pathogens Isolated from Cystic Fibrosis Patients
Cystic fibrosis (CF) patients often acquire chronic respiratory tract infections due to Pseudomonas aeruginosa and Burkholderia cepacia complex (Bcc) species. In the CF lung, these bacteria grow as mu... Read More
- Antimicrobial Activity of Chemokine CXCL10 for Dermal and Oral Microorganisms
CXCL10 (IP-10) is a small 10 kDa chemokine with antimicrobial activity. It is induced by IFN-, chemoattracts mononuclear cells, and promotes adhesion of T cells. Recently, we detected CXCL10 on the s... Read More
- Resistance to Antimicrobial Peptides in Vibrios
Vibrios are associated with a broad diversity of hosts that produce antimicrobial peptides (AMPs) as part of their defense against microbial infections. In particular, vibrios colonize epithelia, whic... Read More
- Occurrence of Ionophores in the Danish Environment
Antibiotics in the environment are a potential threat to environmental ecosystems as well as human health and safety. Antibiotics are designed to have a biological effect at low doses, and the low lev... Read More
- Old and New Glycopeptide Antibiotics: Action and Resistance
Glycopeptides are considered antibiotics of last resort for the treatment of life-threatening infections caused by relevant Gram-positive human pathogens, such as Staphylococcus aureus, Enterococcus s... Read More
- Position-Dependent Influence of the Three Trp Residues on the Membrane Activity of the Antimicrobial Peptide, Tritrpticin
Antimicrobial peptides (AMPs) constitute promising candidates for the development of new antibiotics. Among the ever-expanding family of AMPs, tritrpticin has strong antimicrobial activity against a b... Read More
- Killing of Staphylococci by -Defensins Involves Membrane Impairment and Activation of Autolytic Enzymes
-Defensins are cyclic antimicrobial peptides expressed in leukocytes of Old world monkeys. To get insight into their antibacterial mode of action, we studied the activity of RTDs (rhesus macaque -de... Read More
- Patient Attitudes and Beliefs and Provider Practices Regarding Antibiotic Use for Acute Respiratory Tract Infections in Minya, Egypt
The inappropriate use of antibiotics in the community is one of the major causes of antimicrobial resistance. This study aimed to explore the physician prescribing pattern of antibiotics for acute res... Read More
- Host Antimicrobial Peptides in Bacterial Homeostasis and Pathogenesis of Disease
Innate immune responses function as a first line of host defense against the development of bacterial infection, and in some cases to preserve the sterility of privileged sites in the human host. Bact... Read More
- The Role of Cationic Polypeptides in Modulating HIV-1 Infection of the Cervicovaginal Mucosa
The mucosa and overlying fluid of the female reproductive tract (FRT) are portals for the heterosexual transmission of HIV-1. Toward the ongoing development of topically applied microbicides and mucos... Read More
- Structure-Dependent Immune Modulatory Activity of Protegrin-1 Analogs
Protegrins are porcine antimicrobial peptides (AMPs) that belong to the cathelicidin family of host defense peptides. Protegrin-1 (PG-1), the most investigated member of the protegrin family, is an ar... Read More
- The Role of Antifungals against Candida Biofilm in Catheter-Related Candidemia
Catheter-related bloodstream infection (C-RBSI) is one of the most frequent nosocomial infections. It is associated with high rates of morbidity and mortality. Candida spp. is the third most common ca... Read More
- Mechanisms of Antimicrobial Peptide Resistance in Gram-Negative Bacteria
Cationic antimicrobial peptides (CAMPs) are important innate immune defenses that inhibit colonization by pathogens and contribute to clearance of infections. Gram-negative bacterial pathogens are a m... Read More
- Augmentation of Cationic Antimicrobial Peptide Production with Histone Deacetylase Inhibitors as a Novel Epigenetic Therapy for Bacterial Infections
The emergence of antibiotic resistance seriously threatens our ability to treat many common and medically important bacterial infections. Novel therapeutics are needed that can be used alone or in con... Read More
- NETs and CF Lung Disease: Current Status and Future Prospects
Cystic Fibrosis (CF) is the most common fatal monogenic disease among Caucasians. While CF affects multiple organ systems, the principle morbidity arises from progressive destruction of lung architect... Read More